Folic acid - for what. How to take folic acid - її melancholy and Skoda How to add folic acid to the female organism
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General information
About melancholy folic acid(Vitamin B 9) people have known for a long time, but only in the last 10 years, doctors began to actively promote prophylactic courses of folic acid intake for women and ailments with cold deficiency.Folic acid takes part in the exchange of speech, in the production of DNA, plays an important role in the synthesis of immune blood cells, and normalizes the function of the herbal tract. For female women, folic acid is very necessary, but oscillates play an important role in the development of the neural tube of the fetus. With a normal level of vitamin B 9, the level of vascular development in the fetus is significantly reduced. In addition, it is necessary for normal growth and development of the placenta.
History
In 1926, the doctor-microbiologist V. Efremov revealed a specific form of undercrowding in pregnant women - megaloblastic anemia. The same vitaminology developed boisterously, a lot of research was carried out on its own knowledge. The greatest respect was given to the food factor. Efremov accurately determined the presence of an anti-anemic factor in the liver tissue - in patients who took products from the liver, they were afraid of a significant polypsy.In 1932, the British physician Williams, who had a rich career in India, having established that some female women, as they suffered from megaloblastic anemia, did not fear a rupture when administering a purified extract of liver cells. However, the females were completely dressed after the inoculation of the unpurified extract. Zvіdsi Vіls zrobyv vysnovok, scho when cleaning znischuvavsya important factor, scho zumovlyuє oduzhannya. Tsya speech was unfailingly seen and took away the name - the Wils factor. Later, yogo was called vitamin M. In 1941, it was established that yogo was rich in spinach and parsley, and yogo was changed to folic acid (in translation from the Latin folium - leaf).
Mechanism dії
Consumed in the body, vitamin B 9 transforms into tetrahydrofolate, which serves as a storage component of rich enzymes, and also takes part in low biochemical reactions, for example, in protein metabolism. As a result, the body synthesizes the necessary amino acids, epinephrine and other factors for the adoption of proteins. Also, vitamin B on May 9 has an effect similar to estrogen - it indicates the correct development of the female reproductive system.The most important thing is that the most important stage of splitting whether a cell was splitting was the splitting of DNA molecules. Vitamin B 9 itself takes an active part in the process of DNA replication. Cream of this, vin plays an important role in the process of synthesis of RNA, amino acids, improving the absorption of saliva. Therefore, a small amount of folic acid is not safe for the client, which is easy to share.
Vіd vnya folієvoї acid deposit mood. She takes a part in the metabolism of such neurotransmitters, like serotonin and adrenaline, which are directly injected into the work of the nervous system.
Folic acid stimulates appetite and takes part in the sighting of hydrochloric acid in the stool.
Need for folic acid
In the liver of a person, sound the deak kіlkіst folacin, as you can get rid of hypovitaminosis for 3-6 months. The body of a mature person will require 0.4 mg of folic acid per doba, with pregnancy during lactation - 0.4-0.6 mg, children of the 1st birthday - 0.04-0.06 mg. With a normal state of the intestinal flora, vitamin B9 can vibrate endogenously.Folic acid and vagity
It is necessary to maintain a normal level of folic acid for a couple of months before the pregnancy rate, to reduce the risk of congenital vascular development of the fetus. Clinical studies have shown that 80% of the vadose can be prevented, so that a woman can replenish the lack of vitamin B 9 more often to vagity.AT Russian Federation It is generally accepted that the requirement of female women without symptoms of deficiency of this micronutrient is 0.4 mg per day. In the period of breastfeeding, it is necessary to increase 0.6 mg per dose.
Under the hour of vagity, the woman’s body is stained with more folic acid, lower to vagity. Vitamin B 9 is not stored in reserve, so it is important to take it out of the day from the old days. It is even more important to increase the necessary amount of folic acid in the first trimester, if the fetal nervous system is developing.
The most important role of vitamin B 9 for the fetus is the development of the neural tube. So I take a part in the renewal and mitosis of cells in the mother's body, zocrema cells internal organs, yakі can be constantly updated.
Already on another tyzhnі vagіtnostі in the embryo begins to actively develop the head brain. The very same way to induce a non-trivial deficiency of vitamin B 9 threatens with serious, often inaccurate reports. Danish micronutrients are necessary for the process of mitosis, which is very important for clitins, which are rapidly dividing and developing (before them, in the first line, neurons and other cells of the nerve tissue are visible), then it is not enough, in the first line, is indicated on the nervous system, develops.
Folic acid takes part in the production of the main blood cells (erythrocytes, leukocytes and platelets), which is important both for the mother's body and for the fetus.
For a normal increase in pregnancy, maintaining a healthy woman and fetus, doctors recommend taking folic acid in the form of tablets 2-3 months before the planned pregnancy and continuing right up to the fall. When administering vitamin B 9, it is necessary to increase the doses recommended by the doctor, but the excess of this micronutrient is not safe, as it is a deficiency.
Vitamin B 9 is the only micronutrient, the role of which in case of vaginess is not underestimated by opponents of synthetic vitamin preparations and other drugs. Tom, navit yakscho you unique be-any medicinal preparations under the hour of vagity, do not be concerned about the course of vitamin B 9, if you want to use the method of prevention - you and your child will be killed against a whole series of untrue risks. However, sometimes it is indicated that it is recognized as a doctor for dosing with the body's needs for folic acid.
Deficiency of folic acid and її inherited
With thermal processing, up to 90% of vitamin B 9 can enter the warehouse of six products. For example, with greased meat, it destroys up to 95% of vitamin B 9, with variant meat and products of dewy growth - from 70 to 90%, with variant eggs - close to half.Deficiency of vitamin B 9 can increase due to low intake in the diet, damage to the absorption of micronutrients in the intestines, or increase consumption in this speech (vagity, lactation period).
The reason for this hypovitaminosis has been expanded - regular attendance alcoholic drinks.
Folic acid deficiency is the most common symptom in pregnant women and children in their first years of life. Deficiency of vitamin B 9 in the fetus develops as a result of deficiency in the mother's body, and in infants - as a result of insufficient intake breast milk.
Deficiency of folic acid in the body of a vagit woman can become a factor in the whole a number of serious damage:
- fetal innocence;
- congenital wadi development;
- Rozum's steel;
- vada development of the neural tube;
- splitting of the ridge (in the fetus);
- wadi development of the circulatory system;
- hare lip or vovcha pasta;
- nedokriv'ya.
Lack of vitamin B 9 which is always accompanied by obvious symptoms. At the same time, according to the results of research, the marriage of folic acid is in 20-100% of people who fallow in the area of residence. This is one of the most widespread hypotaminosis. Prote, navit at the presence of quiet others clinical symptoms.
Folic acid deficiency often leads to the development of pernicious anemia in preterm infants. Increased consumption of vitamin B 9 for a number of pathologies: leukemia, hemolytic anemia, chronic infectious disease, carcinomatosis.
In case of lack of vitamin B 9, megaloblastic anemia develops. With this type of undercrowding, not only do they fall in the place of erythrocytes in the blood, but the activity is broken, the fragments of most of them do not ripen in the cystic brain. If you don’t get enough folic acid, such symptoms develop, such as a decrease in appetite, nervousness, and a lack of strength. Later, vomit, carry-over, alopecia come. Possibly morphological damage to the tongue, the appearance of ridges in the empty mouth and pharynx. Even if you don’t know how to exult, megaloblastic anemia can lead to death.
AT stay rocky After conducting a number of clinical trials, as a result of which it was established that a deficiency of vitamin B 9 disrupts the metabolism of sulfuric amino acids, leading to a fading in the blood of amino acids homocysteine. Homocysteine negatively affects the intima of the vessels, which leads to the appearance of atherosclerotic plaques and increases the risk of heart attacks and strokes.
Impaired absorption of vitamin B 9 can be caused by ailments of the duct, gastroectomy, if the body is deficient in antianemic factors (Castle factors), which are synthesized in the duct. Folic acid can be consumed in the blood only due to anti-anemic factors, but in case of deficiency, folic acid levels in the blood fall.
Folic acid cream, Castle factor to carry cyanocobalamin in the blood. Therefore, taking vitamin B 9 preparations in advanced dosing may lead to failure of cyanocobalamin.
Lack of vitamin B 9 is suspected in case of important pathologies of the liver. In the liver itself, the vitamin transforms into tetrahydrofolate, which takes part in biochemical reactions. Folic acid in its primary appearance is essential for the body.
If the body is deficient in vitamin B 9, the hematopoiesis system may be damaged: red blood cells are underripe, and incompetent cells are released into the bloodstream, which is not healthy to transport the acid. Tse is one of the reasons for the development of the vascular system of the nervous system in the fetus, the fragments of neurons cannot fully grow and develop in the minds of hypoxia.
Together with erythrocytes, the synthesis of leukocytes and platelets is disrupted, which can provoke a decrease in immunity and disrupt blood clotting. In female women, vitamin 9 deficiency can be accompanied by a severely deficient state. Tse zbіshuє rizik like a mother, so a child.
Deficiency of vitamin B 9 can develop with lack of vitamins in the diet, starvation, pretreatment unbalanced diets for weight loss. However, the most widespread factor of non-availability of vitamin B 9 is dysbacteriosis. Dysbacteriosis develops after a trivial, often uncontrolled intake of antibiotic drugs, incl. without recognition of a doctor.
In the United States, there is a law, it’s necessary to add a small amount of vitamin B 9 to the borosno, with a method of preventing non-stagnant speech in people who are ill. In the United States, a prophylactic dose of vitamin B is 9 in women, lower in the Russian Federation.
Foods to fight folic acid
Vitamin B 9 to enter the warehouse of all human tissues, creatures, growths and microorganisms. The human body does not produce folic acid. That's why it won't come out of your stomach, otherwise it will be vibrated by the microflora of the intestines. Therefore, in case of impaired bowel function or dysbacteriosis, the production of vitamin 9 may be insufficient. In such situations, a micronutrient additive is needed.Vitamin B 9 to take place at the great kilkost in the dewy hedgehog: spinach, cibula, krip, parsley, kvassola, peas, buckwheat, oats, visivki, bananas, hairy pea, grapefruit, dried apricots, dinya, drіzhdzhі, garmelon, mushrooms, beet, ripa and іn.
Also serve as a source of folic acid meat that is a product of a creature's diet: yalovichina, lamb, pork, liver, nirki, poultry meat, milk, eggs, trout, perch, sir and іn.
A plate of cereal porridge with milk and a bottle of orange juice fill up 50% of the additional consumption of the body in vitamin B9.
Implantation of bifidobacteria stimulates endogenous absorption of folic acid in the intestine.
Vitamin В 9 to finish milky rozpadaєtsya under the influx of sony prominenya and simply with a threefold savings, as well as with temperature processing of products. More likely to collapse folic acid, which is to be avenged in a growing hedgehog. Folic acid in meat is more steak.
Therefore, in order to save vitamin in products, it is recommended to save the diet. Vegetables are the most comfortable with looking at six salads. For such a salad, it is best to add cabbage, parsley, krip, beet leaves, mint or kulbabi. It is also corny to add young nettles to the salad. It is better to drink orange and tomato juices - they have the most folic acid.
Sered meat products Most folic acid is found in the liver. The liver can be lightly smeared and not boiled for long - with the help of vitamin B9, which enters the warehouse, it does not collapse.
Take care of folic acid
folic acid tablets- the best dosage form for dosing (one tablet contains 1 mg of speech). In addition, the most economical option for today. In order to restore the deficiency of the vaginal woman in vitamin B9, it is sufficient to take 1 tablet per day. However, against the background of folic acid deficiency, which may not show up, 2-3 months before pregnancy in the first trimester, you can take 2-3 tablets per day. Such dosing is recommended by physicians, overdose due to such a quantity of the drug is not possible, and the effects of folic acid deficiency are extremely unsafe. In this situation, the doctors go to the point of true reinsurance.Folic acid is released from the drug Folacin. In one tablet, the drug contains 5 mg of vitamin B9. It’s worth more for a day’s norm to get for a vaginal woman. Too much folic acid does not cause either positive or negative effects, but is simply excreted into the body. 1 tablet Apo-folk also take 5 mg of vitamin B 9 . Vrakhovyuchi podvishcheniya vmist speech in tablets, Folacin and Apo-Folik zastosovuyutsya only with acute and severe vitamin deficiency. Z metoyyu prophylaxis qi drugs are not recommended.
In one tablet of the drug Folio take 0.4 mg of vitamin B 9 and 0.2 mg of iodine. The advantage of this drug form is that it can take two micronutrients, so there is no need for supplemental administration of iodine preparations. The dose of vitamin B 9 in one tablet is not high, so it is recommended as a prophylactic drug. Folio is not prescribed for acute deficiency, or for advanced folic acid requirements.
Vitamin B9 to enter the warehouse of polyvitamin preparations for vitamins. Contains folic acid in one tablet skin preparation - different:
- Materna - 1 mg;
- Elevit - 1 mg;
- Vitrum prenatal - 0.8 mg
- Vitrum prenatal forte - 0.8 mg
- Multi-tabs perinatal - 0.4 mg
- Pregnavit - 0.75 mg.
Vitamin B 9 is acquired much more quickly than medicinal preparations, lower food products.
Cream of pharmaceutical preparations, folic acid can be taken from biologically active additives.
Indication
Folic acid is indicated for advancing camps:- folic acid deficiency anemia;
- anemia as a complication after gastroectomy;
- sprue (tropical diarrhea);
- chronic inflammation of the intestines;
- intestinal tuberculosis;
- vaginess;
- lactation period;
- vitamin B deficiency 9 .
- it is possible to watch for signs of folic acid deficiency (in this case, dosing is prescribed by the doctor individually);
- yakscho іsnuyut factors that increase the need for vitamin B 9 or stimulate yogo excretion from the body.
- implantation of combined oral contraceptives before conception;
- implantation of Maalox chi Phosphalugel;
- taking anticonvulsants during the planning period and during pregnancy;
- protein diet before conception;
- a lack of dewy hedgehogs in a tavern;
- damage to the grass tract;
- vomit with vaginess.
Clinical trials have demonstrated that vitamin B 9 may have a positive effect in the prevention of Alzheimer's disease. In individuals with this pathology, as a rule, there is a decrease in the amount of folic acid and cyanocobalamin in the blood.
Method of stosuvannya that dose
If a woman is present, if it is due to divine factors, then during the planning period of pregnancy in the first trimester, it is necessary to take 2-3 mg of vitamin B 9 per day. Also, taking the drug at an advanced dosage is necessary for the high degree of damage to the development of the neural tube. Such a risk is in women with epilepsy, diabetes, and also for the presence of similar disorders in relatives in a straight line.Requirement for folic acid with vaginess - 0.4 - 0.8 mg per doba. However, with a deficient state of dosing, it significantly increases with the method of compensating for lack of vitamin. The neural tube of the embryo begins to develop at 3-5 tyzhnі vagity. At this hour, a woman may not know about vaginess and not take her own course of compensation for folic acid deficiency. Therefore, vitamin B9 is necessary to take 1-3 months before the ovulation. It is more important to increase the necessary amount of folic acid in the first trimester.
Folic acid should be taken during lactation at a rate of 0.3 mg per day (possible with a multivitamin complex). Tse to serve as a preventive course for both mothers and children. If you administer the drug in higher doses (eg, 1 mg), then the amount of vitamin will simply be introduced into the body of a woman, not in a bad way, not a malyukov.
It is important to increase the regularity of the intake of vitamin B 9 . However, those who need to take a dose in any preparation, who exceed the daily need for vitamins, skipping one dose is not guilty of anxiety.
- Atherosclerosis. 5 mg of vitamin 9 per doba for two days, then 1 mg each. It is recommended to live as a B-group vitamin complex.
- Aphthous stomatitis. As a rule, afti (virazki on the mucosal membranes of the mouth) are at once cracked on the lips with a deficiency of vitamins and micronutrients, which take the fate of hematopoiesis. Among them: vitamin B 9, zalizo and cyanocobalamin. The recommended dosing is 5 mg of vitamin B 9 3 times per dose of 10 mg of glycinate saliva for 120-180 days. Once every 30 days to work with cyanocobalamin - 1 mg. During the walk, it is necessary to regularly review the cyanocobalamin rhubarb.
- Viral hepatitis. Folic acid zastosovuetsya as an additional zasib. It is recommended to take 5 mg 3 times per doba for a total of 10 deb, then 5 mg per doba.
- Gingivitis and periodontitis. Take orally 1 mg of vitamin B 9 times per day, rinsing the empty mouth 2 times per day for one whilin 1% of vitamin B, 60-70 deb.
- Depression. Often poserіgaєtsya in osіb іz deficiency of folic acid. Take 2-5 mg daily in the complex with B-group vitamins.
- Osteochondrosis. Vitamin B 9 takes part in the collagen framework, which accumulates calcium salts. Without a collagen framework, the cyst does not acquire the necessary minerality. Recommended dosing - daily 5 mg vitamin B 9, 50 mg vitamin B6, 50 mg vitamin B-complex.
- Puhlina of the larynx. Even if some of your relatives are on a straight line of illness on the basis of oncological illness, it is strongly recommended to take 1-5 mg of vitamin B 9 and 100 mg of vitamins in the B-complex once for production.
- Spasm of the intestines. They appear at the sight of constipation and carry, colic and bloating of the stomach. Lack of vitamin B9 can lead to chronic constipation, which can lead to intestinal spasm. It is necessary to start with 10 mg of the vitamin once per day. Even after 15-20 days, there is no progress, so increase the dose to 20-60 mg per dose to a positive effect. Dalі dozuvannya stepwise decrease. It is recommended to take 0.1 g of B-complex vitamins once per hour. During the course, it is necessary to regularly review the cyanocobalamin rivulet. In the diet, it is recommended to include white coats in order to avenge the water resistance of the cellular tissue. Wheat vines are not suitable for any occasion, for those whose veins are indistinct.
- Epilepsy. After an attack of epilepsy, vitamin B 9 decreases in the brain. Anticonvulsants also reduce plasma concentrations. As a result, attacks become more frequent. For epilepsy, prescribe 5 mg per doba. Prote take the drug only after consultation with the doctor.
Overdose
Overdosing is very rare. For whom, the organism is guilty of taking hundreds of times more for the necessary amount of folic acid (20-30 mg). With an insignificant overdose of the necessary amount of the drug, excess folic acid is excreted without causing any harm to the body. At the same time, like a medicine, vitamin B9 preparations can alleviate allergies.Serious minus of taking vitamin B 9 preparations in those who develop symptoms of megaloblastic anemia, and also suffer from neurological damage, associated with this disease. Therefore, with a trivial intake of preparations of vitamin B 9, the progression of important neurological disorders could be attributed to the lack of cyanocobalamin. For the past 10 years, it has been taken into account that there is no overdose of this micronutrient. However, at the same time, according to reports, as it is known about those who have been implanted in women with vitamin B 9 in advanced dosing, children with weak immunity, susceptibility to bronchial asthma and colds.
Hypervitaminosis
Increased doses of vitamin B 9 can provoke a child's dyspepsia or increase anxiety. It is not recommended to try the vitamin in the advanced dosing, shards can bring cyanocobalamin in the blood to death.Side effects
Depending on the individual tolerability of folic acid preparations, it can cause allergic manifestations, bronchospasm, reddening of the skin, hyperthermia, visip.Vitamin B 9 does not cause a toxic injection on the human body. Clinical follow-ups were conducted on a three-fold intake of vitamin B 9 at a dose of 15 mg per day (in 40 times more than the body needs). According to the results of the study, the drug did not repair any toxic disease. However, prolonged intake (more than 90 days) of vitamin B 9 in advanced dosing can lead to a drop in the level of cyanocobalamin in the blood, which can provoke anemia. Increased doses of vitamin can provoke disorder of the herbal tract, increase anxiety, cause imbalance in robotics.
Active preparations reduce the amount of vitamin B 9 in blood plasma. Among them:
- acetylsalicylic acid (in advanced dosing);
- nitrofurani (taken for infections of sich paths);
- combined oral contraceptives;
Folic acid for a healthy person
Vitamin B 9 is essential for women and men. With chronic vitamin deficiency, people may develop low pathologies, including benign megaloblastic anemia. Taking folic acid in a therapeutic dose, including similar complications.The main indicator of human health is considered to be spermatozoa. Spermatozoa are also cells that are required for the synthesis of proteins and nucleic acids. For the presence of vitamin B 9, the synthesis of spermatozoa is disrupted. When the vitamin is not enough, the concentration of spermatozoa changes and becomes worse: spermatozoa can have an unnatural shape, or not a tail, which changes their fragility. Moreover, such spermatozoa may have an incorrect number of chromosomes, and may be the main factor in the decline of ailments in children (for example, Down's syndrome).
Vitamin B 9 and the hormone testosterone contribute to the normal development of spermatozoa. Folic acid is extremely important for people in the puberty period, but it is one of the factors in the development of secondary state signs (roughness in voice, growth in appearance and body, intensive growth).
Folic acid in treatment and prevention of oncological diseases
Vitamin B 9 prevents oncological illness. However, if the illness has already begun, then the drug cannot be used, folic acid shards are acceptable under the skin and cancerous cells. In similar situations, medications are used, which would take into account the activity of vitamin B 9, for example, methotrexate. Tse galmuє zbіlshennya puhlinya. To prevent damage to the exchange of speech, prescribe a drug that replaces vitamin B 9 - folic acid. Because of the higher risk of cancerous disease in people of a frail age, they are not recommended to take folic acid preparations without the recommendation of a doctor.Leucovorin is a medicinal product based on folic acid, which is successfully used in the warehouse of chemotherapy for oncological diseases. Vіn reduce the severity of intoxication after the ingestion of cytostatic preparations (vomiting, carryover, hyperthermia, damage to the cystocerebral tissue).
The rest of the studies of the United States have brought the intake of drugs to vitamin B 9 and the progression of the swollen intestines.
Since 1980, the Harvard skin 2 roki ruled the field, which took the fate of approximately 90,000 women and children. Meals were eaten and okremo to the recipient of vitamin complexes. In 1994, the selected information was seriously tested for the incidence of colon cancer, the third most common type of cancer among women in the United States. Experimental data showed that women who took enough vitamin B 9 - more than 0.4 g mg per day, most suffered from the same illness.
Vcheni have grown wisnovok: 75% of the swelling of the swollen intestines in women can be lost, as a protracted life to live in prophylactic doses of vitamin B9.
Doslіdzhennya allowed to add one more important visnovok. Most of the time, the tuft of the tympanic intestine was bulging in women, and for the rest of 10-15 years, vitamin complexes were regularly implanted.
Folic acid and prevention of atherosclerosis
In the rest of the hour, the doctors of the daedals are more likely to think that folic acid is effective in the prevention of atherosclerosis - the main cause of heart-vascular disease.Today, a new theory of the pathogenesis of atherosclerosis is popular in Zakhod. Vіdpovіdno to tsієї teorії, main cause progression of atherosclerosis high rіven in the blood, not all known cholesterol, but another bioactive factor - homocysteine.
Homocysteine is a ceendogenic amino acid. Under the influence of enzymes in the body, it is transformed into the essential fatty amino acid methionine, which takes part in the production of protein. As the body suffers from a deficiency of other enzymes, homocysteine accumulates in the blood and the ruined walls of blood vessels, causing inflammation. Cholesterol takes part in this process at a greater number of stages. Adherents of the new theory argue that atherosclerosis does not progress without homocysteine for an increased level of cholesterol in the blood.
What is the role of folic acid in this key? On the right, in that it is itself necessary for the synthesis in the body of enzymes that transform homocysteine into methionine. Deficiency of vitamin B9 leads to a deficiency of a vital enzyme. As a result, homocysteine accumulates in the blood, which leads to the progression of atherosclerosis, and then worsens - ischemia of the heart, heart attack, stroke.
Before zastosuvannyam, you should consult with a faculty member.Any other marriage failing the necessary functions. In such a case, a component can be added to a synthetic look.
The next report was to analyze the main functions of the vitamin, to understand, now to drink folic acid.
- It helps in preparation before conception and wins a significant role in the development of the fetus.
- Improve your memory.
- Improves the process of old.
- Supports the development of children.
- Improves symptoms in menopause.
- Knowing drativity.
- Prevents thrombosis.
- Relieve anemia.
- Normalize the psyche.
Speech takes an active part in the enlightenment of red blood cells, in the regulation of nerve impulses, and in prompting cells.
The complex with vitamins B12 can reduce the risk of eye disease by 30%. Folic acid is injected into the skin, increasing and developing tissues, normalizing the work of the immune system and supporting the heart-vessel.
Lack of language in women can lead to the fact that the reproductive organs are not properly energized by estrogen. What is worth to the human body, folic acid is similar to testosterone, helping to vibrate sperm. For the development of a normal voice timbre in a person, the growth of the beard and the functioning of the prostate, vitamin B9 is indispensable.
Measles due to folic acid intake and Skoda overdose were noted. The positive injection of vitamin E is not transverse, but it is not necessary to allow too much of it. Drink vitamin B9 preparations only after consultation with a physician, and less in case, as an additional method of speaking is effectively necessary.
Flat-cylindrical buns in pale-yellow to yellow color, with chamfered tassel. The appearance of interspersed dark and light colors is allowed.
stock
Skin tablet revenge fluent speeches: folic acid - 1 mg; additional speeches: zucrova powder, potato starch, stearic acid.
Pharmacotherapeutic group
Anti-anemic protection. Folic acid and її pokhіdnі. ATX code: B03BB01.
Pharmacological authorities
Pharmacodynamics
Vitamin B group (vitamin B9) can be synthesized by intestinal microflora. In the body, folic acid is converted to tetrahydrofolic acid, which is a coenzyme that takes part in various metabolic processes. It is necessary for the normal maturation of megaloblasts and the establishment of normoblasts. Stimulates erythropoiesis, taking part in the synthesis of amino acids (including glycine, methionine), nucleic acids, purines, pyrimidines, in the exchange of choline, histidine.
Pharmacokinetics
Folic acid, which is prescribed in the eyes medical care, good and povno vmoktuєtsya at the shlunkovo-intestinal tract, most importantly at the upper vіddіlakh 12-colon intestine (for the obviousness of the syndrome of malabsorption on aphids of the tropical sprue, at the same time the folate folate is nasty in the syndrome of malabsorption). Intensively binds with plasma proteins. Penetrates through the blood-brain barrier, the placenta and into breast milk. TC max - 30 - 60 min.
It is deposited and metabolized in the liver with approved tetrahydrofolic acid (in the presence of ascorbic acid and dihydrofolate reductase). It is important to administer nirkami as metabolites; If the dose taken significantly exceeds the additional requirement for folic acid, then it should be taken in the future. Seek help for hemodialysis.
Do you need mother's mental nerves, deep sleep, normal hemoglobin, calm stress and less likely to get sick with a cold? Who will help you with folic acid. Її retribution for the body next discuss the report. Proponuemo zrobity tse right now.
From the life of vitamins: how is folic acid used in the body? For men - it is shown, for women - it is necessary! How to understand, what time to drink folacin? Do you need some yoga? De shukati vitamin B9 and how to take yoga? The effect, but not the one they counted on!
From the life of vitamins: how is folic acid used in the body?
Її іnshe іm'ya - vitamin B9 or folacin. A positive impact on the body of folic acid was observed in 30 years of the last century. And people learned how to use this synthetic way in the 40s of the last century. The main work of folacin is to support the growth of cells in the body. For this very reason, yoga is especially important in the period of growth - if the little one grows up in the mother’s tummy, in the child’s pіdlіtkovu vіtsі. Ale folic acid is necessary and mature. The organism stores such speech in the liver. If so, the reserves are not replenished, blaming the deficit.
Diya vitamin B9 on the body
- reduce the risk of stroke, heart attack, heart pathologies;
- spriyaє fermentation of enzymes, yakі zapobigayut development of new products;
- spray serotonin (hormone of joy);
- guarantee the stability of the nervous system;
- spryaє more productive rozumovіy diyalnostі;
- positively influences the functioning of the liver, intestines;
- improve immunity;
- virіvnyuє vice;
- taking part in the synthesis of amino acids;
- activate blood circulation;
- take an uninterrupted fate in hematopoiesis;
- improve memory;
- ensure the delivery of carbon for the synthesis of hemoglobin;
- help the body cope with stress;
- ensure the transmission of the nerve impulse;
- increases the speed of exchange processes, stimulates active spalling of fats, thereby reducing weight loss;
- give a healthy looking hair, improve your vipadance;
- paint the burning mill.
For men - it is shown, for women - it is necessary!
Now let's look at the value of vitamin B9 for human and female health. Representatives of the strong state will be at the god's end all the more pronounced lusciousness of acid acid. Ale not only! Folic acid can improve the quality of sperm (destroy the spermatozoa more ruinously) in order to increase the reproductive health of a person and increase the possibility of conceiving a healthy baby. For young people, such a component should be ensured by the correct ripening, in due course the appearance of secondary signs.
It is very important for a woman to get acquainted with this vitamin at the stage of planning the pregnancy and the hour of wine making for a child. It is impossible to overestimate the value of folic acid for the body as it is maybe mami, and її fetus. Tsya speech is vvazhaetsya as a guarantee of a normal overshoot of vagity and the birth of a healthy baby. It ensures that the neural tube is properly molded and does not prevent the appearance of congenital anomalies of the brain, heart disease, and various anatomical defects. Folic acid protects and protects against frontal canopies.
Important! Navit z urahuvannyam її tsіnnostі uncontrolled intake of this vitamin with vaginostі categorically fenced! Yogo is too good for the development of asthma in children!
Folacin is necessary for new mothers to stabilize the emotional background and prevent the development of post-mortem depression. It is even more important to drink folic acid for girls, as they take anti-parasitic drugs, because they sound like a shortage. This vitamin reduces menstrual flow, normalizes the cycle. Adult women also need folic acid. Її remorse for the body is connected with centuries of perebudov. It is ahead of early menopause, galmues antiquity, protects the appearance of sivine and smoothes the symptoms of menopause.
How to understand, what time to drink folacin?
Indirect evidence that the body has a supply of vitamin B9 and symptoms. You can suspect such a problem, so that you spend the whole hour in a hushed mood, feel unreasonable anxiety, fear, confusion and forgetfulness. On the deficiency of the language of speech, they indicate a bright-red zabarvlenny tongue, inflamed mucous membrane of the mouth, damaged etching, appearance. gray hair enough young vice. In children, it is possible to have a look at the growth. Girls-podlitkivs have a stutter of state maturity.
Indications for taking folic acid are vaginess. And yet, a couple of months before the planned date of conception, the future father (and man, and woman) may start drinking such an additive. This drug is prescribed for anemia, as caused by B9 deficiency. Yogo vikoristovuyut in treatment of chronic gastroenteritis, intestinal tuberculosis, tropical diarrhea SPRU.
Do you need some yoga?
There is no single norm. Here everything is laid up for a long time and I will become people. The number of such speeches is reduced by micrograms, which makes one millionth part of a gram.
Additional norms of folates:
- women "at the position" - 600 mcg each;
- with lactation - 500 mcg;
- mature - 400 mcg;
- malyukovі to rock - 50 mcg;
- children up to 3 years - 100 mcg;
- from 3 to 10 years - 150 mcg;
- pіdlіtkam - 200 mcg.
De shukati vitamin B9 and how to take yoga?
One of the most important factors that "vote" for folic acid intake are those that the body is not able to grow independently. Folate supplements can be buti products. Wine is found in city greenery, peas, vegetables (including beet, carrot, broccoli, artichoke, asparagus), barley groats, sucrose, red ribs, baked goods, chicken, pork, mushrooms, fruits.
Ale vzhivat їх sіd less for the orphan looking. If a heat-treatment were to speed up instead of such a speech to a meagerly small quantity, it would be impossible to take away the meat of the meat. And in vegetables and fruits today, more often nitrates, lower wholesome components are accumulated.
If you do not know how to compensate for the need for folic acid for additional products, you can use it for additional bioactive drugs, as they are sold in pharmacies in the form of tablets, ampoules, powder. Let's figure out how to take folic acid for the body. Tablets can be taken at a dose of 1 mg (1000 mcg). Їhnya k_lk_st in the package to become 25-50 pcs. Standard health care dosing for women and people - 1 tab. for production, with a likuvalny method - vіd 2 to 5 tab. at day.
For women, a special supplement is “folic acid 9 months”, where 0.4 mg is taken in one tablet. Call them to assign for such a scheme: 1-2 tables. nicely. Children are recommended to make a walk near the water and in the water required quantity drug for the help of a syringe
Drink such bioadditives next to the process or after that, in order to reduce their drativity on the tube. Like a chergovy acceptance of vipadkovo omissions, there is no trace of a subwinning portion. Liki, yakі neutralize shlunkovu acidity, it is required to drink not earlier than in 2 years after the introduction of vitamin B9. "Tetracycline", "Neomycin", "Polymyxin" reduce the absorption of folates.
Important! It is not enough to put folacin into the body. It is necessary to take care of it. To that end, it should be taken together with vitamin B12.
The effect, but not the one they counted on!
Vrahovyuchi such a viable mission, as if victorious in the body, you may develop an attack, the more you drink folacin, you will become a healthy person. Ale tse zovsіm negarazd. An excess of such a building speech cannot be healed, but seriously bad.
Durability for taking folacin:
- hanging on the floor;
- development of allergies;
- peresbudzhennya, dramativism;
- no nightmares;
- sudomi;
- carrying;
- call until you puke.
Important! Above the world's intake of folic acid in the body of a person who smokes, the greater the risk of the appearance of evil spirits.
Contraindications and contraindications before taking folic acid - individual intolerance, lack of vitamin B12, hemochromatosis.
It doesn’t matter to our body what we do, but it’s important that we have a variety of vitamins and minerals necessary for its functioning, the plants are like biochemical processes. One of the most important vitamins for humans is folic acid, also vitamin B9. Most people need folic acid, why can’t you live without it, and more importantly, in what foods can folic acid be found? Today is our rozmova about tse.
Folic acid is another name for vitamin B9. This water-soluble vitamin is often produced by the clitins of our intestines, part of it should be called at the same time from the same, yak mi їmo.
The name of the vitamin resembles the Latin word Folium, which in translation means a leaf. The same substance was first seen from spinach leaves in 1941 by a group of acclaimed Indian-American biochemist Yellapragadi Subbarao.
What is the need for folic acid?
Vitamin B9 may life important meaning for our body, and won't be bad,
- if the organism requires the growth of the metabolism;
- take part in the formation of an embryo on the first tizhnya of yogo development;
- pours into the process of hematopoiesis;
- reshuffling of thrombi in blood-bearing vessels;
- spryya rejuvenation, shards permanently replace cells on top of our body.
Let's take a closer look at how folic acid works in the body.
With vagity
According to the recommendations of daily obstetrics, folic acid should be taken by all women, if they plan to be pregnant at least 3 months before conception and the first 3 months after conception of a child. How are these recommendations grounded?
- Vitamin B9 is important for the overall synthesis of DNA and proteins, without which rozpodil clitin cannot be used. In the period of vagity, the need for folic acid increases sharply, if the clitin of the embryo and the development of the fetus are intensively affected;
- Folic acid is of great importance in the laying of organs. After the conception of the first stage of development of the embryo, it is necessary to lay the neural tube - the possible nervous system in the brain of a child;
- Cream molding of organs in the fetus is molded cystic brain those elements of hematopoiesis (erythrocytes, leukocytes, thrombocytes);
- Stasis of folic acid before and after conception by 70-75% decreases the risk of development of the nervous system, the development of the nervous system duct-intestinal tract that heart-vascular system;
- Nucleic acids, which are synthesized in addition to folic acid, are added to the process of transmission of depression traits.
Deficiency of folic acid in the body of a vagit woman can lead to a risk of development of various malformations and calculi in the fetus (hydrocephalus, canine pascha, hare lip, myocardial hernia, defects in the cardiovascular system and the vertebral column), as well as taking stillbirths. normally displaced placenta. Nadal in a child may be afraid of a physical chirozoum development.
If the slope is too low, the woman can also detect traces of folic acid insufficiency. Lack of vitamin reduces the production of the hormone serotonin, which leads to depression, bad mood, lack of strength, lack of sleep, which leads to insufficient amount of breast milk. The baby is not found, and a decrease in the concentration of folic acid in breast milk can lead to the development of anemia, vasodilation, reduced immunity, disruption of the intestines, psychomotor galvanism.
For women
For young women, folic acid helps to establish a regular menstrual cycle, improving mood and self-esteem. And yet, folic acid is a beautiful vitamin, which contributes to the process of rejuvenation. She herself constantly replaces the shkiri, which have died, with new ones, helping for the obviousness of the visips and the covers on the skin, peeling and increasing the fat content of the shkiri.
I will improve my nails and hair, the roblyachi will be healthy and radiant, they will avoid the frizziness and lupi on the hair.
Okremo I will designate the need for folic acid intake for women in the menopausal period. At the same time, in women after 50 years, the production of hormones in extragens decreases in women. Folic acid may have an ekstrogen-like effect on the body, which is why there are a lot of unacceptable symptoms in menopause less pronounced:
- The frequency decreases, the frivolity and the severity of the tides, to which the sweating and the feeling of heat change, attacks of tachycardia appear;
- The sweat is changing
- Polypshuetsya, becomes a calm sleep;
- Normalization of arterial pressure;
- Pollipshuetsya moods, lowering the level of depression.
In addition, when folic acid is stagnant, the risk of developing macular degeneration, contagion decreases, which manifests itself as a network breakdown and a decrease in the severity of the disease, anemia and such ailments of CT, such as gastritis, celiac absorption and malabsorption.
Next to know, sho, zastosovayuchi overnight antiseptic tablets, Glucocorticosteroids, nitrofurans, antacids, aspirin, vitamins in the body will be badly conquered.
For people
Do not varto ignore this vitamin and people. The cream of a globally positive impact on the body as a whole, is important for people and also on the plan of the total reproductive work of the body. Bagato hostile factors(Ecological situation, stress, shrill sounds, improper eating) Aje for healthy offspring, a healthy organism is needed, which vibrates all the spermatozoa. Spermatozoa, such as cells, which are necessary for their synthesis of proteins and nucleic acids. Folic acid for people increases the chances of conceiving that people healthy kids, so like
- there is a greater number of total spermatozoa: together with testosterone, a normal development of spermatozoa is observed;
- the number of spermatozoa changes, which can cause genetic mutations, which can eventually lead to Down syndrome, schizophrenia, epilepsy in children.
For these reasons, planning the woman's pregnancy, folic acid intake should be recommended to men. Of particular importance is the stagnation of this vitamin during the period of the state maturation of young people, the development of secondary state signs is observed: coarsening of the voice, growth of hair on the face and body, intensive growth.
Prevention of atherosclerosis
Today at the scientific medical stakes Western countries A popular theory is the development of atherosclerosis, for which a high level of bioactive homocysteine, an endogenous amino acid, is added to the pathogenesis of the disease.
Under the influence of enzymes in the body, it is transformed into the essential fatty amino acid methionine, which takes part in the production of protein. As the body suffers from a deficiency of other enzymes, homocysteine accumulates in the blood and the ruined walls of blood vessels, causing inflammation.
In this way, platelets and excess cholesterol are glued to the inflamed and streaked walls of the vessels, making thrombosis and cholesterol plaques. Folic acid causes and changes the development and progression of atherosclerosis. And tse nasampered prevention of ischemic heart disease and morbid complications - heart attacks and strokes.
With oncology
Z vіkom immune system a person knows the songs of change, becomes immune to various infections and cancer. It is firm, that vitamin B9 is ahead of the growth of fluff. However, even though the pathological process is already gone, folic acid, on the other hand, provokes cancer cells.
The rest of the hour is to spend a lot of time to add folic acid to the growth of cancerous puffs. The results are ambiguous, the axis of the display is the results of the results published in various medical journals.
October 2013, The Lancet magazine. In his press release, the author of an interview with the University of Oxford, Robert Clark, said:
Canadian researchers from St. Michael's Medicine (Toronto), Zocrema, Dr. En-In-Kim, the leading author of the study, showed that folic acid preparations, like taking patients with breast cancer, can take the most common diseases.
In June 2009, the Journal of the National Cancer Institute published the results of a study of the relationship between folic acid and risk factors for the development of prostate cancer. A student at the University of California, the author of the report, Jane Figueiredo, found that taking vitamin supplements with folic acid increases the risk of developing prostate cancer more and more.
In 2006, a doctorate at the Catholic University of the Sacred Heart established that taking large doses of folic acid will help regress leukoplakia of the larynx (a precancerous disease that precedes cancer of the larynx).
Keep in mind especially for summer people, and remember when you need it, taking medications with vitamin should be strictly following the doctor's recommendation.
Signs of folic acid deficiency
How can you tell if your body is deficient in vitamin B9? Show respect, as you have such signs:
- bad moods, dramatization and depression;
- headache, which is accompanied by weakness, difficulty in breathing;
- problems with storing information;
- the appearance of unacceptable clues and the names of the sentences;
- soreness in an empty mouth, the appearance of a vein and an increased tongue;
- such diarrhea;
- macrocytic anemia.
Obviously, there is no need to engage in self-admiration. With the appearance of a cih sign, nevertheless, consult a doctor first, go through an obstezhennya.
Signs of an overdose of vitamin B9
At obvious crusty This does not mean that preparations with folic acid can be instilled successfully. If the water-soluble vitamin is easily excreted all at once from the body, an overdose of the drug can be. And for whom it is necessary to take a dose that will outweigh the dobov in 100 times.
Even though an overdose occurred in women at the hour of fetal vinification, then in the future, such children may develop scalability to colds and bronchial asthma.
Children who have taken away folic acid may react with dyspepsia and increased alertness, and people who may have pathology of the cardiovascular system may react with coronary insufficiency.
Too much vitamin can be manifested by the following symptoms:
- the company has a hot metal prismak;
- restless mood and disturbed sleep;
- disruption of the robotic PCT (nudity, to the point of vomiting, a rare stiletto, grumbling in the abdomen);
- Appearing visipu on the skin covers;
- In ailments with epilepsy, it is possible to appear in court;
- disruption of the function of nirok;
- Symptoms that are blamed for deficiency of zinc and vitamin B12 (decreased immunity, anemia thinly).
How to receive and dose
Do not varto spodіvatisya more than on the instruction from the prescription of the drug. In case of different pathologies, the dosage of the drug can be different, so the recommendations of the doctor here will be more direct. It is important to know what doses can lead to resistance (switching).
Optimal additional dose for zastosuvannya:
- For newborns - no more - 0.1 mg;
- Children in age up to 4 years - 0.3 mg;
- Children at age 4 and older - 0.4 mg;
- At breastfeeding- 0.6 mg
- The period before conception and the first hour of pregnancy - 0.4 mg;
- In case of folic acid deficiency anemia, independantly in vіk -1.0 mg, nadіl the dose may be adjusted.
The dose of the drug is due to be established in an individual order and in mothers of a clear cold in the period of pregnancy, in breastfeeding, in oncologists.
The course of the drug taken is not guilty of revisiting no more than a month. The effectiveness of the drug decreases with one-hour administration of alcohol, sulfonamides, other antibiotics, antacid drugs.
Foods to fight folic acid
Folic acid enters the warehouse of tissue growth and creatures, but the human body does not synthesize yoga. That is why we need a lot of vitamins and we need to call for it, otherwise it is vibrated by microflora in the large intestine. Improvement of the disease process can reveal intestinal dysfunction and dysbacteriosis. In this type of deficiency, it is necessary to fill it with special preparations, for example, bifidobacteria to help stimulate the production of folic acid in the intestine.
List of products rich in vitamin B9:
- Roslinna їzha - spinach, cabbage, asparagus, lettuce, beetroot, turnip, rice, peas, oats, visivka, wheat, peas, nasinnya, herbs, citrus fruits;
- Dairy products - milk, cheese, cheese;
- Meat is a product of the creature's journey, rich in vitamins in offal - nirkah, bakery, bird meat. Especially rich in folic acid in chicken liver;
- Fish, especially salmon, that seafood;
- Pivnі drіzhdzhi, mushrooms.
It is important to know that vitamin B9 is already rapidly collapsing under the influx of sony exchanges, during thermal processing of products and with a drastic recovery. Therefore, in order to save the cinnamon component, it is best to use fresh products, if possible, in salads.
The daily norm can be filled with a portion of salad with fresh young spices, city greens, cabbage, kulbabi leaves, beetroot, mint. І drink orange and tomato juice.
Dear readers, today you have recognized what folic acid is, why it is so important for our health. Get used to more products, which will take care of vitamin B9, and then your health and your future and right children will be precious, and you yourself will be deprived of young and beautiful for a long time. Be healthy!
Fahіvtsami brought the value of folic acid for women, especially for future mothers. Vitamin B9 is water-spreading rechovina (folate), as it takes part in DNA and biosynthesis of proteins. This is an important element, necessary for the life of our entire body. First, yogo was grown from a single herbaceous growth - spinach.
Folic acid: what is good for women?
Folacin takes part in the development, renewal of blood cells (leukocytes, erythrocytes) and exchange of speech. Therefore, a valuable vitamin is necessary for future mothers for:
- shaping a healthy fetus;
- zabіgannya defects yoga development;
- relief of symptoms of toxicosis;
- reduced risk of placental insufficiency and anterior canopies.
According to the findings, folic acid is essential for the female body:
- polypshenya blood circulation and metabolism;
- reduction of ignition processes;
- promotion of immunity;
- sharpened memory;
- improvement of hair cibulins;
- upovіlnennya old shkіri;
- relief of unacceptable symptoms in menopause;
- promotion of hemoglobin (prevention of thrombosis, chronic deficiency anemia);
- innovation of herbal processes;
- removal from the body of otters, slags, toxins;
- reduced risk of breast cancer, ovarian cancer.
Folic acid, also necessary for young girls – vitamin koriguє stateevé maturation, ahead of the appearance of acne, pimples.
Important: failure of the “female” element to cause serotonin to decrease, as a result of which the vitality decreases, drativity appears, depressive states develop.
Dzherela folic acid
The largest amount of the element is concentrated in dark green trees, fruits and vegetables, as it is recommended to live with an orphan who does not look shabby. Representatives of the beautiful state for the improvement of health (physical, rosum) and the promotion of susceptibility should include in the menu the following products with folacin:
- broccoli, wild garlic, selera, asparagus, spinach, lettuce, green cibula;
- pea hairs, almonds, peanuts, fresh watermelon;
- pressing, dry yeast, germinated wheat, visivki;
- mint leaves, raspberries, motherboards, shipshini;
- zhovtki eggs, homemade milk, liver, brunki, meat, sea fish;
- avocado, citrus.
Also, special supplements are used, vitamins with folic acid for women, as they are taken according to the instructions.
Important: folic acid is the most corrosive when taken with vitamin B12.
How to inject a lack of folic acid on the female organism
Deficiency of element B9 can lead not only to an increase in stagnation and a decrease in efficiency, but also to:
- disruption of hematopoietic processes and the work of the central nervous system;
- simplification of the hour of vacancy;
- early sivin;
- reduced immunity;
- appearance of cancer cells;
- problems from etching and memory;
- atherosclerosis;
- complications in the cardiovascular system;
- shkirny ill;
- early menopause.
Lack of folacin is most often blamed for anemia, in patients with alcohol poisoning, taking medical preparations (sechoginn, protizaplidni).
Who needs folic acid in January?
The brown element is shown to be taken by active people who go in for sports, as well as:
- nedokriv'ya;
- vagity;
- stunts of state development;
- menopause;
- parts of a cold;
- with supra-mundane rozumovyh preoccupations, stresses, mental disorders.
The optimal supplementary norm for grown-ups is 250-500 mg, for children - 50-150 mg in the fallow season. The risk of hypovitaminosis is small, folacin is not toxic to the body.
Be healthy!
